Published

2024年
  • Flores KA, Okada A, Arce F Jr, See GL, Itakura S, Todo H, Sugibayashi K. Development of an Auraptene-Loaded Transdermal Formulation Using Non-ionic Sugar Ester Surfactants. Chem Pharm Bull (Tokyo). 2024;72(3):319-323. doi: 10.1248/cpb.c23-00796. PMID: 38508724.
    https://www.jstage.jst.go.jp/article/cpb/72/3/72_c23-00796/_html/-char/en

  • Futaki M., Inamura K., Nishimura T., Niitsu T., Tojo T., Sugibayashi K., Todo H.,A Hollow Microneedle Equipped with a Micropillar for Improved Needle Insertion and Injection of Drug Solution.Pharm Res. 2024 Mar 5. doi: 10.1007/s11095-024-03681-7. Online ahead of print.
    https://link.springer.com/article/10.1007/s11095-023-03529-6
2023年
 
  • Sugibayashi K.,The role of higher education in pharmacy and pharmaceutical sciences in addressing global warming: A personal perspective.,JOURNAL OF ASIAN ASSOCIATION OF SCHOOLS OF PHARMACY - Volume 12, January - December 2023.,Pages: 38-46
    https://link.springer.com/article/10.1007/s11095-023-03529-6

  • Niki Rina, Akie Okada, Hiroaki Todo, Ibuki Narita, Kazuya inamura,Shoko itakura,Ichiro Hijikuro and Kenji Sugibayashi.,Development of a depot formulation with an in situ non-lamellar liquid crystal-forming system with phospholipids.,Front. Drug Deliv., 19 October 2023
    https://www.frontiersin.org/articles/10.3389/fddev.2023.1270584/full

  • Inoue Y, Ueda S, Tanikawa T, Sano A, Suzuki R, Todo H, Higuchi Y, Akao K.,Characterization of Carbohydrates, Amino Acids, Viscosity, and Antioxidant Capacity in Rice Wines Made in Saitama, Japan, with Different Sake Rice.,Foods. 2023 Nov 1;12(21):4004. doi: 10.3390/foods12214004.PMID: 37959123 Free PMC article.
    https://www.mdpi.com/2304-8158/12/21/4004

  • Sekiguchi S,Narita I,Itakura S,Kojima H,Sugibayashi K,Todo H.,Evaluation of Skin Permeation Order of Cosmetic Active Compoundsfrom Commercially Available Cosmetic Products with Different Dosage Forms Using a Three-Dimensional Cultured Human Skin Model.,Accepted: June 2, 2023
    https://jcss.jp/journal/pdf/4703/47-3_176.pdf

  • Takayama K, Itakura S, Todo H, Sugibayashi K.,Prediction of Critical Quality Attributes Based on the Numerical Simulation of Stress and Strain Distributions in Pharmaceutical Tablets.,Chem Pharm Bull (Tokyo). 2023;71(6):386-397. doi: 10.1248/cpb.c22-00539.,PMID: 37258191
    https://www.jstage.jst.go.jp/article/cpb/71/6/71_c22-00539/_html/-char/en

  • Futaki M, Inamura K, Hashimoto M, Motegi S, Itakura S, Sugibayashi K, Todo H.,Effects of Intradermal Administration Volume Using a Hollow Microneedle on the Pharmacokinetics of Fluorescein Isothiocyanate Dextran (M.W. 4,000).,Pharm Res. 2023 May 10. doi: 10.1007/s11095-023-03529-6. Online ahead of print.,PMID: 37165148
    https://link.springer.com/article/10.1007/s11095-023-03529-6

  • Takayama K, Itakura S, Todo H, Sugibayashi K.,Prediction of Critical Quality Attributes Based on the Numerical Simulation of Stress and Strain Distributions in Pharmaceutical Tablets.,Chem Pharm Bull (Tokyo). 2023;71(6):386-397. doi: 10.1248/cpb.c22-00539.
    https://pubmed.ncbi.nlm.nih.gov/37258191/

  • Oshizaka T, Hayakawa M, Uesaka M, Yoshizawa K, Kamei T, Takeuchi I, Mori K, Itakura S, Todo H,Sugibayashi K.,Design of an Ante-enhancer with an Azone-Mimic Structure using Ionic Liquid.Pharm Res. 2023 Apr 20. doi: 10.1007/s11095-023-03515-y. Online ahead of print.
    https://link.springer.com/article/10.1007/s11095-023-03515-y

  • Itakura S, Shohji A, Amagai S, Kitamura M, Takayama K, Sugibayashi K, Todo H.,Gene knockdown in HaCaT cells by small interfering RNAs entrapped in grapefruit-derived extracellular vesicles using a microfluidic device.,Sci.Rep.,2023 Feb 22;13(1):3102.
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947018/

  • Mori K, Yamazaki K, Takei C, Oshizaka T, Takeuchi I, Miyaji K, Todo H, Itakura S, Sugibayashi K.,Remote-controllable dosage management through a wearable iontophoretic patch utilizing a cell phone.,J. Control.Release 2023 Mar;355:1-6.
    https://www.sciencedirect.com/science/article/pii/S016836592300055X

  • Kojima H, Nakada T, Yagami A, Todo H, Nishimura J, Yagi M, Yamamoto K, Sugiyama M, Ikarashi Y, Sakaguchi H, Yamaguchi M, Hirota M, Aizawa S, Nakagawa S, Hagino S, Hatao M.,A step-by-step approach for assessing acute oral toxicity without animal testing for additives of quasi-drugs and cosmetic ingredients,Curr Res Toxicol. 2022 Dec 23;4:100100. eCollection 2023.
    https://pure.fujita-hu.ac.jp/en/publications/a-step-by-step-approach-for-assessing-acute-oral-toxicity-without

  • Ito A, Itakura S,Hasegawa Y,Hashimoto M,Okada A, Hirafuji M,Nakamura H,Sugibayashi K an, Todo H.,Usefulness of direct intratumoral administration of doxorubicin hydrochloride with an electro-osmosis–assisted pump .,Front. Drug Deliv., 04 April 2023
    https://www.frontiersin.org/articles/10.3389/fddev.2023.1150894/full

2022年
  • Inoue Y, Ishizawa M, Itakura S, Tanikawa T, Todo H., Verification of nanoparticle formation, skin permeation, and apoptosis using Nobiletin as a methoxyflavonoid derivative, AAPS Open, 8, 17 (2022).
    https://aapsopen.springeropen.com/articles/10.1186/s41120-022-00065-2

  • Sakurai H, Suzuki M, Itakura S, Todo H, Arce F V Jr, See GL, Tanikawa T, Inoue Y., Preparation, Characterization, Solubility, and Antioxidant Capacity of Ellagic Acid-Urea Complex, Materials,15, 2836 (2022)
    https://www.mdpi.com/1996-1944/15/8/2836

  • 藤堂浩明,半固形製剤からの薬物の経皮吸収についての考え方 (半固形製剤特集),製剤機械技術学会会誌, 31, 16-24 (2022).


  • Ono N, Iibuchi T, Todo H, Itakura S, Adachi H, Sugibayashi K., Enhancement of skin permeation of fluorescein isothiocyanate-dextran 4 kDa (FD4) and insulin by thermalporation, Eur. J. Pharm. Sci., 170, 106096 (2022).
    https://www.sciencedirect.com/science/article/pii/S0928098721003973?via%3Dihub

  • Hama S, Nishi T, Isono E, Itakura S, Yoshikawa Y, Nishimoto A, Suzuki S, Kirimura N, Todo H, Kogure K. Intraperitoneal administration of nanoparticles containing tocopheryl succinate prevents peritoneal dissemination.Cancer Sci.,113, 1779-1788 (2022).
    https://onlinelibrary.wiley.com/doi/10.1111/cas.15321

  • Okada A, Niki R, Inoue Y, Tomita J, Todo H, Itakura S, Sugibayashi K. Development of Self-Administered Formulation to Improve the Bioavailability of Leuprorelin Acetate.(2022)
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9031317/

  • Kunita R, Nishijima T, Todo H, Sugibayashi K, Sakaguchi H.A Mathematical Approach Using Strat-M® to Predict the Percutaneous Absorption of Chemicals under Finite Dose Conditions.(2022)
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318111/

  • Kojima H, Nakada T, Yagami A, Todo H, Nishimura J, Yagi M, Yamamoto K, Sugiyama M, Ikarashi Y, Sakaguchi H, Yamaguchi M, Hirota M, Aizawa S, Nakagawa S, Hagino S, Hatao M.A step-by-step approach for assessing acute oral toxicity without animal testing for additives of quasi-drugs and cosmetic ingredients.(2022)
    https://www.sciencedirect.com/science/article/pii/S2666027X22000378?via%3Dihub

  • Sano T, Okada A, Kawasaki K, Kume T, Fukui M, Todo H, Sugibayashi K. Self-Assembled Structure of α-Isostearyl Glyceryl Ether Affects Skin Permeability-a Lamellar with 70-nm Spaces and L3 Phase Enhanced the Transdermal Delivery of a Hydrophilic Model Drug.(2022)
    https://link.springer.com/article/10.1208/s12249-022-02452-0

  • Kamimura M, Inui T, Mouri A, Todo H, Sugibayashi K, Asano K. A Pilot Study of Transdermal Application of Diphenhydramine to the Nasal Ala in Patients with Allergic Rhinitis and Asthma.(2022)
    https://pubmed.ncbi.nlm.nih.gov/36420548/

2021年
  • 藤堂浩明,外用薬の皮膚透過と混合の影響 (特集 手元に 1 冊! 皮膚科混合・併用薬使用ガイド), デルマ（全日本病院出版会）, 314,9-15（2021）
  • Sasaki D, Kusamori K, Takayama Y, Itakura S, Todo H, Nishikawa M. Development of nanoparticles derived from corn as mass producible bionanoparticles with anticancer activity. Sci. Rep., 24, 11, 22818 (2021).
  • Liao CC, Wu CY, Lin MH, Hsieh FK, Hsu LT, Chang SY, Chen KJ, Huang HT, Hsu HC, Lin CH, Lin PJ, Lai HM, Kojima H, Todo H, Lin SJ, Li JH, Chen W. Validation study of a new reconstructed human epidermis model EPiTRI for in vitro skin irritation test according to OECD guidelines.Toxicol. In Vitro., 75,105197 (2021).
  • H Kojima, T Nakada, A Yagami, H Todo, J Nishimura, M Yagi, M Sugiyama, K Yamamoto, Yi Ikarashi, Hi Sakaguchi, M Yamaguchi, M Hirota, H Ikeda, N Imai, M Hatao. Step-by-Step Approach for Assessing Human Skin Irritation Without Animal Testing for Quasi-Drugs and Cosmetic Products. Applied In Vitro Toxicology.7, 144-154 (2021).
  • Abe A, Suzuki H, Amagai S, Saito M, Itakura S, Todo H, Sugibayashi K.Effect of Rubbing Application on the Skin Permeation of Active Ingredients from Lotion and Cream.Chem. Pharm. Bull.,69,806-810(2021).
  • Katayama H, Maeda Y, Sato T, Mogi A, Itakura S, Todo H, Sugibayashi K, Takayama K.Design and Optimization of Scored Tablets with Concave Surface and Application of Bayesian Estimation for Solving Scaleup Problem. Chem Pharm Bull.69, 1088-1096(2021).
  • Katayama H, Itakura S, Todo H, Sugibayashi K, Takayama K. Latent Structure Analysis of Wet-Granulation Tableting Process Based on Structural Equation Modeling. Chem Pharm Bull. 6, 674-680(2021).
  • Mori K, Usuzaka E, Oshizaka T, Takei C, Todo H, Sugibayashi K. Use of Silicone Membrane Permeation to Assess Thermodynamic Activities of Ionic Liquids and Their Component Cation and Anion.Chem Pharm Bull., 69, 481-487 (2021).
  • 藤堂 浩明, 齋藤 美幸, 鈴木 宏宙, 井上 裕, 高山 幸三, 杉林 堅次.各種市販ミノキシジル製剤の安全性・有効性に及ぼす容器の種類の影響.薬剤学, 81 , 111-120 (2021).
  • Todo H, Hasegawa Y, Okada A, Itakura S, Sugibayashi K. Improvement of Skin Permeation of Caffeine, a Hydrophilic Drug, by the Application of Water Droplets Provided by a Novel Humidifier Device.Chem Pharm Bull.69:727-733 (2021).
  • Mitsuhiro Kamimura; Takako Ohnishi; Hisao Terada; Atsuto Mouri; Takahiro Naoi; Hiroaki Todo; Kenji Sugibayashi.Application of diphenydramine ointment to the eyelids for allergic conjunctivitis.BEROAMERICAN JOURNAL OF MEDICINE.01.44-50 (2021).
  • Suzuki T, Aoki T, Saito M, Hijikuro I, Itakura S, Todo H, Sugibayashi K.Enhancement of Skin Permeation of a Hydrophilic Drug from Acryl-Based Pressure-Sensitive Adhesive Tape.Pharm Res., 38, 289-299 (2021).
  • Okada A, Todo H, Itakura S, Hijikuro I, Sugibayashi K.A Lipid-Based Depot Formulation with a Novel Non-lamellar Liquid Crystal Forming Lipid.Pharm Res., 26,1-11(2021).
  • Sugibayashi K, Futaki M, Hashimoto M, Fukuhara A, Matsumoto K, Oshizaka T, Itakura S, Todo H. Effect of Iontophoresis on the Intradermal Migration Rate of Medium Molecular Weight Drugs Chem.Pharm. Bull, 69, 639-645 (2021).
2020年
  • Sugibayashi K, Yamamoto N, Itakura S, Okada A, Hijikuro I, Todo H, Development of spray formulations applied to the oral mucosa using non-lamellar liquid crystal-forming lipids,Chem Pharm Bull,68, 1025-1033 (2020).
  • 杉林 堅次, 森 健二, 押坂 勇志, 武井 千弥, 藤堂 浩明, 板倉 祥子, 高山 幸三.感染から治癒過程を表現する「感染症数理疫学」と吸収から消失過程を表現する「薬物動態学」の類似点と相違点.薬剤学, 80 , 322-329 (2020).
  • See GL, Arce F Jr, Dahlizar S, Okada A, Fadli MFBM, Hijikuro I, Itakura S, Katakura M, Todo H, Sugibayashi K. Enhanced Nose-To-Brain Delivery of Tranilast Using Liquid Crystal Formulations.J. Control. Release, 325, 1-9 (2020).
  • Abe A., Suzuki H., Saito M., Todo H., Sugibayashi K. Effect of rubbing on the distribution of topically applied drugs into the hair follicles. Chemical and Pharmaceutical Bulletin, 68,832-836(2020).
  • See GL., Arce F Jr., Itakura S., Todo H., Sugibayashi K. Prolonged distribution of tranilast in the eyes after topical application onto eyelid skin. Chemical and Pharmaceutical Bulletin, 68,779-783(2020).
  • Sugibayashi K., Yoshida Y., Suzuki R., Yoshizawa K., Mori K., Itakura S., Takayama K., Todo H. Physical Properties of an Ionic Liquid Composed of Two Water-Soluble Vitamins and Enhanced Skin Permeation of Both Vitamins. Pharmaceutics.12(5):E427 (2020).
  • Arce F Jr., Asano N., See GL., Oshizaka T., Itakura S., Todo H., Sugibayashi K. Prediction of skin permeation and concentration of rhododendrol applied as finite dose from complex cosmetic vehicles.Int J Pharm., 578, 119186. (2020).
  • Arce FJ., Asano N., See GL., Itakura S., Todo H., Sugibayashi K. Usefulness of Artificial Membrane, Strat-M®, in the Assessment of Drug Permeation from Complex Vehicles in Finite Dose Conditions.Pharmaceutics, 12. 173 (2020)．
  • Okada A., Todo H., Hijikuro I., Itakura S., Sugibayashi K., Controlled release of a model hydrophilic high mollecular weight compound from injectble non-lamellar liquid crystal formulations containing different types of phospholipids.,Int.J.Pharm.,577, 118944 (2020).
2019年
  • Iikura H, Uchida K, Ogawa-Fuse C, Bito K, Naitou S, Hosokawa M, Uchida T, Sano T, Todo H, Sugibayashi K, Effects of temperature and humidity on the skin permeation of hydrophilic and hydrophobic drugs, AAPS PharmSciTech, 20, 264 (2019)
  • 藤堂浩明， 足立浩章， 今井教安， 上中麻規子， 内田崇志， 大谷道輝， 澤田美月， 成田昌稔， 西島貴史， 野村宜史， 宮坂美行， 畑尾正人， 増永卓司， 山口雅彦， 佐々齊， 知久真巳， 川田裕三， 古屋律子， 藤井まき子, 無限用量にて適用した種々剤形からのカフェインの皮膚透過性と皮膚内濃度の関係について—ヒト長期投与 (安全性) 試験の用量設定法ガイドライン策定のための検証結果 その 2—,日本香粧品学会誌, 43, 183-190 (2019).
  • Sugibayashi K, Yusuf E, Todo H, Dahlizar S, Sakdiset P, Arce FV Jr, See GL, Halal cosmetics: A review on ingredients, production, and testing methods, Cosmetics, 6, 37 (2019)
  • Hatanaka T, Saito T, Fukushima T, Todo H, Sugibayashi K, Umehara S, Takeuchi T, Okamura Y, Potential of biocompatible polymeric ultra-thin films, nanosheets, as topical and transdermal drug delivery devices, Int J Pharm, 565, 41-49 (2019).
  • 藤堂浩明， 足立浩章， 今井教安， 上中麻規子， 内田崇志， 大谷道輝， 澤田美月， 成田昌稔， 西島貴史， 野村宜史， 宮坂美行， 畑尾正人， 増永卓司， 山口雅彦， 佐々齊， 知久真巳， 川田裕三， 古屋律子， 藤井まき子, 無限用量にて適用した種々剤形からのイソプロピルメチルフェノールの皮膚透過性と皮膚内濃度の関係について—ヒト長期投与 (安全性) 試験の用量設定法ガイドライン策定のための検証結果 その 1—, 日本香粧品学会誌,43, 99-108 (2019).
  • Okada A., Todo H., Hijikuro I., Itakura S., Sugibayashi K., Controlled release of a model hydrophilic high mollecular weight compound from injectble non-lamellar liquid crystal formulations containing different types of phospholipids., Int. J. Pharm., (2019) Dec 21:118944 .
  • Sugibayashi K., Yusyf E., Todo H., Dahlizar S., Sakdiset P., Arce F.V.J.,SeeG.L., A Review on Ingredients, Production, and Testing Methods, Cosmetics (2019), 6, x.
  • Takamaya K., Sato T., Sato K., Todo H., Obata Y., Sugibayashi K., Prediction of tablet characteristics based on sparse modeling for residual stresses simulated by the finite element method incorporating Drucker-Prager cap model,JDDST ,52, 1021-1031 (2019).
  • See G.L., Sagesaka A., Todo H., Wierzba K., Sugibayashi K., Pharmacokinetics and Tissue Distribution of Pilocarpine After Application to Eyelid Skin of Rats, J. Pharm. Sci., 108, 2942-2948 (2019).
  • Arce FV Jr, Asano N, Yamashita K, Oda A, Uchida T, Sano T, Todo H, Sugibayashi K. Effect of layered application on the skin permeation of a cosmetic active component, rhododendrol. J Toxicol Sci.44, 1-11 (2019).
2018年
  • Sugiyama M., Sugibayashi K., Todo H., Hagino S., Omori T., Imai N., Toyoda A., Ikeda H., Akita M., Okamoto Y., Okumura H., Ohno Y., Comparative assessment of 24-h primary skin irritation test and human patch test data with in vitro skin irritation tests according to OECD test guidelines 439 (for quasi-drugs in Japan), JTS, (2018).
  • Dahliar S., Futaki M., Okada A., Yatomi C., Todo H., Sugibayashi K., Combined use of N-Palmitoyl-Glycine-Histidine gel and several penetration enhancers on the skin permeation and concentration of metronidazole,Pharmaceutics, (2018).
  • See G.L., Sagesaka A., Torizuka H., Todo H., Sugibayashi K., Iontophoresis-aided drug delivery into the eyeball via eyelid skin, JDDST., (2018).
  • Todo H., Tamura M., Uchida T., Kurumada M., Motoki A., Sano T., Onuki Y., Takayama K., Sugibayashi K., Prediction of skin permeation of flurbiprofen from neat ester oils and their o / w emulsions, Chem. Pharm. Bull., (2018).
  • Suzuki T., Sakisako Y., Kurihara Y., Aoki T., Kanematsu T., Todo H., Sugibayashi K., Development of drug-in-adhesive patch with a honeycomb film as a backing layer, Chem. Pharm. Bull., (2018).
  • Todo H., Sato K., Takayama K., Sugibayashi K., Optmization of Premix Powders for Tableting Use, Chem. Pharm. Bull., 66, 748-756 (2018).
  • Dahlizar S., Futaki M., Okada A., Kadhum W.R., Todo H., Sugibayashi K., Design of a topically applied gel spray formulation with ivermectin using a novel low molecular weight gelling agent, palmitoyl-glycine-histidine, to treat scabies, Chem. Pharm. Bull.,66, 327-333 (2018).
  • Abe A, Saito M, Kadhum WR, Todo H, Sugibayashi K, Establishment of an evaluation method to detect drug distribution in hair follicles, Int J Pharm, 542, 27-35 (2018).
  • Sakdiset P, Okada A, Todo H, Sugibayashi K, Selection of phospholipids to design liposome preparations with high skin penetration-enhancing effects, JDDST, 44, 58-64 (2018).